Anticancer and Free Radical Scavenging Competence of Zinc Oxide Nanoparticles Synthesized by Aqueous Leaf Extract of Phyllanthus acidus

The purpose of this study was aimed to investigate the zinc oxide nanoparticles (ZnONPs) synthesizing efficiency aqueous leaf extract Phyllanthus acidus. Furthermore, antioxidant and anticancer activities synthesized ZnONPs were also investigated through in-vitro approach. obtained results show that P. acidus can synthesize ZnONPs, as evidenced by a sharp absorbance peak at 375 nm. Fourier transform infrared spectroscopy (FTIR) analysis confirmed contained significant numbers functional groups, which involved in reducing nitrate into ZnONPs. Also, they participate capping stabilization their size ranged from 27.14–35.74 nm with spherical shape . ABTS radical scavenging activity 1, 1-diphenyl-2-picryl-hydroxyl (DPPH), hydrogen peroxide (H2O2), 2,2′-Azino-Bis(3-ethylbenzene thiazoline-6-sulfonic acid) (ABTS) assays declared has excellent radicals reasonable IC50 values. Interestingly, these green have an against human epidermoid carcinoma (Hep3) cell line These findings imply be used pharmaceutically valuable To consider such nanomaterials potential therapeutic agents, optimization in-vivo biomedical studies are required.